Bertinoro, Italy
15-21 April 2018

 

Programme

  • Sunday, 15 April

    16:30-17:30 Arrival and registration
    17:30 Welcome ceremony
    Introduction to the school, general information, and assignment of students to Agora teams
    18:30 Welcome drinks followed by buffet dinner
  • Monday, 16 April

    9:00-9:45 David Attwell (University College London • London, UK)
    Astrocyte calcium signalling and neuronal function - is there a connection?!
    [30 min + 10 min discussion]
    9:45-10:30 Richard Robitaille (Université de Montréal • Montreal, QC, Canada)
    Excitability of astrocytes: calcium signalling
    [30 min + 10 min discussion]
    10:30-10:50 Coffee break
    10:50-11:35 Elly Hol (UMC Utrecht • Utrecht, Netherlands)
    Astrocytes in health and disease: tools to study human astrocytes
    [30 min + 10 min discussion]
    11:35-12:10

    Student presentations
    [7 min + 3 min discussion each]

    Christiaan Huffels (Utrecht, Netherlands)
    Amyloid-beta induced changes in synaptic transmission during early stage Alzheimer's disease

    Janssen M. Kotah (Amsterdam, Netherlands)
    The role of astrocytes in the early-life stress induced changes in Alzheimer’s disease pathology in transgenic APP/PS1 mice

    Kevin L. Batenburg (Amsterdam, Netherlands)
    Astrocytes in a human model of tauopathy

    12:10-12:30 Agora • Preparation (1)
    12:30-14:00 Lunch break
    14:00-14:35

    Student presentations
    [7 min + 3 min discussion each]

    Elena Scremin (Padua, Italy)
    Ca2+ dyshomeostasis in familial Alzheimer’s disease: role of Orai2 in store-operated Ca2+ entry

    Mislav Majnarić (Padua, Italy)
    Neuron-glia interactions in neurovascular coupling

    Ákos Menyhárt (Szeged, Hungary)
    Potassium wave of spreading depolarization initiates arteriolar constriction in the mouse cerebral cortex

    14:35-15:20 Inbal Goshen (The Hebrew University of Jerusalem • Jerusalem, Israel)
    Expand your toolbox!
    [30 min + 10 min discussion]
    15:20-16:15

    Student presentations
    [7 min + 3 min discussion each]

    Mark W. Sherwood (Bordeaux, France)
    Contribution of IP3Rs to astrocytic Ca2+ signalling and hippocampal long-term potentiation

    Anurag Singh (Dunedin, New Zealand)
    Heterodendritic metaplasticity in the hippocampus – a role for astrocytes?

    Serena Riccitelli (L'Aquila, Italy)
    Effects of Bmal1 gene deletion in astrocytes on retinal morphology and physiology

    Davide Gobbo (Homburg, Germany)
    Role of glial transmitter receptors in network function and neuron-glial interactions in absence seizures

    Rosa Chiara Goisis (Padua, Italy)
    Astrocytes and GABA tonic inhibition as key targets in Dravet Syndrome

    16:15-16:35 Coffee break
    16:35-17:20 Alfonso Araque (University of Minnesota • Minneapolis, MN, USA)
    Specific tools for astrocyte stimulation
    [30 min + 10 min discussion]
    17:20-18:05 Giorgio Carmignoto (CNR Istituto di Neuroscienze • Padua, Italy)
    Optogenetic tools to study neuron-to-astrocyte signalling
    [30 min + 10 min discussion]
    18:05-19:00

    Student presentations
    [7 min + 3 min discussion each]

    Márton Péter (Budapest, Hungary)
    The role of astrocytes in epilepsy: identification of new drug targets

    Ivana Rosenzweig (London, United Kingdom)
    Neuroinflammation in obstructive sleep apnoea

    Steven Condamine (Montreal, QC, Canada)
    Astrocytic networks define functional domains in brainstem circuits responsible for jaw movements

    Ludovica Iovino (Florence, Italy)
    ATP, astrocytes and central respiratory control in the lamprey

    Rodrigo A. Lerchundi (Düsseldorf, Germany)
    Correlation between activity-dependent sodium signalling and ATP levels in neurons and astrocytes

    20:00 Dinner
  • Tuesday, 17 April

    9:00-9:55

    Student presentations
    [7 min + 3 min discussion each]

    Ana Armada-Moreira (Lisbon, Portugal)
    Platinum nanoparticle-based microreactors as support for neuroblastoma cells

    Christina Ioannidou (Bordeaux, France)
    Involvement of astroglial CB1 receptors in psychotic-like states induced by acute or chronic THC administration

    Barbara Genocchi (Tampere, Finland)
    Mathematical model on neuron-astrocyte interaction during epileptic seizures

    Gebhard Stopper (Homburg, Germany)
    Analysis of Ca2+-signals in mice

    Anna Capano (Paris, France)
    Role of astrocytes in cocaine addiction

    9:55-10:40 Inbal Goshen (The Hebrew University of Jerusalem • Jerusalem, Israel)
    Bi-directional modulation of recent and remote memory by astrocytes
    [30 min + 10 min discussion]
    10:40-11:00 Coffee break
    11:00-12:05

    Student presentations
    [7 min + 3 min discussion each]

    Lidia Giantomasi (Genoa, Italy)
    Circadian rhythms: can astrocytes transmit circadian informations among neuronal populations?

    Graziella Di Cristo (Montreal, QC, Canada)
    P75NTR activation in inhibitory parvalbumin cells regulates their connectivity and promotes ocular dominance plasticity in adult visual cortex

    Eva Lasič (Ljubljana, Slovenia)
    Fusion pore modulation of astroglial vesicles with ketamine and dynamin

    Denisa Koleničová (Prague, Czech Republic)
    Age-related changes in astrocyte swelling and their volume regulation

    Anthony Bosson (Montreal, QC, Canada)
    Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells

    Aina Badia Soteras (Amsterdam, Netherlands)
    Proteomic investigation of perisynaptic astrocyte proteins

    12:05-12:50 Arlette Kolta (Université de Montréal • Montreal, QC, Canada)
    Methods to assess astrocytic coupling and its influence on neuronal networks
    [30 min + 10 min discussion]
    12:50-14:15 Lunch break
    14:15-15:00 Harald Sontheimer (Virginia Tech Carilion Research Institute • Roanoke, VA, USA)
    Biophysical properties of astrocytes and how to study them
    [30 min + 10 min discussion]
    15:00-15:55

    Student presentations
    [7 min + 3 min discussion each]

    Noémie Mazaré (Paris, France)
    Local protein synthesis in perisynaptic astroglial processes and its physiological implication in learning

    Carl-Philipp Meinung (Regensburg, Germany)
    Oxytocin dynamically regulates astrocytic gap-junction proteins in vivo and in vitro

    Irene Molina (Edinburgh, United Kingdom)
    Investigating the role of astrocytes in remyelination in the central nervous system 

    Samira Samtleben (Edmonton, AL, Canada)
    Role of oxidoreductase ero1α in neuroinflammatory astrocytes of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE)

    Brandon Stopnicki (Montreal, QC, Canada)
    Helper CD4+ T cells expressing granzyme B cause glial fibrillary acidic protein fragmentation in astrocytes in an MHCII-independent manner

    15:55-19:00 Agora • Preparation (2)
    [with coffee]
    20:00 Pizza party
  • Wednesday, 18 April

    9:00-9:45 Christine Rose (Heinrich Heine University Düsseldorf • Düsseldorf, Germany)
    Imaging of intracellular sodium in the rodent brain
    [30 min + 10 min discussion]
    9:45-10:30 Frank Kirchhoff (University of Saarland • Homburg, Germany)
    Transgenic mouse models for astrocyte and NG2 glia research
    [30 min + 10 min discussion]
    10:30-11:00 Coffee break
    11:00-11:45 Giovanni Marsicano (INSERM • Bordeaux, France)
    Behavioural studies: between data and interpretations, the winner is...
    [30 min + 10 min discussion]
    11:45-12:30 David Attwell (University College London • London, UK)
    Calcium signalling in oligodendrocytes and microglia
    [30 min + 10 min discussion]
    12:30-14:00 Lunch break
    14:00 Departure to Ravenna
    Sightseeing and guided tours, followed by dinner
    Return to Bertinoro after dinner
  • Thursday, 19 April

    9:00-9:45 Richard Robitaille (Université de Montréal • Montreal, QC, Canada)
    Glial mismanagement of neuromuscular junction structure and function
    [30 min + 10 min discussion]
    9:45-10:30 Giovanni Marsicano (INSERM • Bordeaux, France)
    Roles of astroglial type-1 cannabinoid receptors in the brain: focus on bioenergetics
    [30 min + 10 min discussion]
    10:30-11:00 Coffee break
    11:00-11:45 Giorgio Carmignoto (CNR Istituto di Neuroscienze • Padua, Italy)
    Astrocytes as functional components of interneuron type-specific brain circuits
    [30 min + 10 min discussion]
    11:45-12:30 Arlette Kolta (Université de Montréal • Montreal, QC, Canada)
    Mechanisms by which neuron-astrocyte interactions modulate the network output
    [30 min + 10 min discussion]
    12:30-14:00 Lunch break
    14:00-14:45 Harald Sontheimer (Virginia Tech Carilion Research Institute • Roanoke, VA, USA)
    Malignant astrocytes
    [30 min + 10 min discussion]
    14:45-15:30 Elly Hol (UMC Utrecht • Utrecht, Netherlands)
    Reactive astrocytes in brain disease: do they affect neuronal communication?
    [30 min + 10 min discussion]
    15:30-19:00 Agora • Preparation (3)
    [with coffee]
    20:00 Dinner
  • Friday, 20 April

    9:00-9:45 Francesco Papaleo (Istituto Italiano di Tecnologia • Genoa, Italy)
    The Dysbindin-1A isoform modulates basal ganglia-related phenotypes through astrocytic-dependent functioning
    [30 min + 10 min discussion]
    9:45-10:30 Frank Kirchhoff (University of Saarland • Homburg, Germany)
    (Patho)-Physiological properties of astrocytes in vivo
    [30 min + 10 min discussion]
    10:30-11:00 Coffee break
    11:00-11:45 Christine Rose (Heinrich Heine University Düsseldorf • Düsseldorf, Germany)
    Astrocyte sodium signalling under physiological and pathophysiological conditions
    [30 min + 10 min discussion]
    11:45-12:30 Alfonso Araque (University of Minnesota • Minneapolis, MN, USA)
    Circuit-specific synaptic regulation by astrocytes
    [30 min + 10 min discussion]
    12:30-14:00 Lunch break
    14:45-19:00 Agora
    [with coffee]
    19:00-19:30 General discussion, Concluding Remarks, Questionnaires
    20:00 Farewell Dinner
  • Saturday, 21 April

      Departure